Information for Doctors

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Thoracic Medicine

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Sleep Medicine

Latest News

TSGQ registered nurse and polysomnographic technician Travis Bell joined 612 ABC radio presenter Kelly Higgins-Devine to discuss sleep disorders on 2nd February 2015.

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Scientists have found that that activation of cholinergic neurons - those that release the neurotransmitter acetylcholine -- in two brain stem structures can induce REM sleep in an animal model. Better understanding of mechanisms that control different sleep states is essential to improved treatment of sleep disorders.

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Going to bed early could help individuals avoid repetitive negative thinking, according to a recent study. According to the authors, repetitive negative thinking is "defined as an abstract, perseverative, negative focus on one's problems and experiences that is difficult to control."

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In a recent US study results indicated that poor sleep may be an early warning sign for addictive and “regretful” behaviour; such as alcohol problems, illicit drug abuse and sexual behaviour. US researchers reviewed the sleep patterns of 6500 adolescents in combination with drug and alcohol habits, between 1994 and 2002.

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Scientists at the Medical College of Wisconsin (MCW) have discovered a link between sleep loss and cell injury. Results of a new study find sleep deprivation causes the damage to cells, especially in the liver, lung, and small intestine. Recovery sleep following deprivation heals the damage.

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New research confirms that sleep disturbances are linked to pain and depression, but not disability, among patients with osteoarthritis (OA).  Results from a new study found that poor sleep increases depression and disability, but does not worsen pain over time.

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Current trials

Patients needed for patent 1, patent 2 and chest clinical trials

PATENT 1, PATENT 2 and CHEST trials are currently underway at the Wesley Pulmonary Hypertension Unit and new patients are required.  We are trialing Riociuguat - a direct stimulator of the soluable Guanylate Cyclase which plays a significant role in the nitric oxide pathway and is intended for the treatment of PH. The trial is in association with Bayer and Wesley Research Institute.

In PATENT 1 & 2 trials, the patient can already be on therapy with an endothelin receptor antagonists (bosentan, sitaxentan or ambrisetan) or naïve to PAH therapy.

The CHEST trial is using the same agent for non-operable chronic thromboembolic disease related PAH.  (CTEPH)

We are accepting patients now for these trials by referral.

About The Wesley Pulmonary Hypertension Unit

The Wesley Pulmonary Hypertension Unit (WPHU) has established itself as one of the largest specialised treatment centres in Queensland.  In just 18 months of operation, the clinic has reviewed patients for treatment and have been actively enrolling patients into international clinical trials.  The treatment programs include monotherapy and combination treatments in keeping with the best available therapies for PAH.

Treatments Available

All PBS funded medications for monotherapy

Combination therapy – funded or via clinical trials

Clinical Trials with WRI

PATENT 1 and 2 trials

CHEST trial

Diagnostic Procedures

Cardiac Catherterisation
Nuclear imaging
MRI and CT
Echocardiograms
Complex Lung Testing CPET
Diagnostic Sleep Studies
6 MWT


The Wesley Pulmonary Hypertension Unit multidisciplinary team includes:

Dr John Feenstra
Thoracic and Sleep Physician
P:  (07) 3876 9033
F:  (07) 3871 3222
E:  This e-mail address is being protected from spambots. You need JavaScript enabled to view it
W: www.thoracicandsleep.com.au

Dr Andrew Scott
Thoracic and Sleep Physician
P:  (07) 3876 8405
F:  (07) 3870 3212
E:   This e-mail address is being protected from spambots. You need JavaScript enabled to view it
W:  www.thoracicandsleep.com.au

Dr David Cross
Cardiologist
P:  (07) 3858 8600
F:   (07) 3870 4917
E:   This e-mail address is being protected from spambots. You need JavaScript enabled to view it
W: www.heartcarepartners.com.au

Helen Woodhouse, CNC
WPHU Coordinator
P:  0404 650 281
F:  (07) 3871 3222
E:   This e-mail address is being protected from spambots. You need JavaScript enabled to view it

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