Information for Doctors

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Thoracic Medicine

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Sleep Medicine

Latest News

The Wall Street Journal reported recently on the topic of sleep deprivation as to which cities around the World are the most and least sleep deprived. Brisbane leads the way with the earliest bed time and earliest wake up time.

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According to new research, risk of being obese by age 21 was 20 percent higher among 16-year-olds who got less than six hours of sleep a night, compared with their peers who slumbered more than eight hours.

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As we get older there is a strong relationship between reduced amount and quality of sleep. Recent research has found specific cluster of neurons that have linked insomnia and more sleep fragmentation. The reduction of these neurons can be from normal aging but has also been seen in Alzheimers disease.

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A bedtime routine might sound like something that's only necessary for the grade-school set, but following a nightly schedule can greatly improve the sleep of adults, too. Sleep experts recommend establishing a bedtime routine, both to calm and relax you as you get ready to sleep and so you aren't inadvertently giving yourself jet lag.

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Researchers at NYU Langone Medical Center and elsewhere, using a mouse model, have recorded the activity of individual nerve cells in a small part of the brain that works as a "switchboard," directing signals coming from the outside world or internal memories. Because human brain disorders such as schizophrenia, autism and post-traumatic stress disorder typically show disturbances in that switchboard, the investigators say the work suggests new strategies in understanding and treating them.

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The death rate from asthma in Australia has fallen by almost 70 per cent since the 1980s, according to a new report released by the Australian Institute of Health and Welfare

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Current trials

Patients needed for patent 1, patent 2 and chest clinical trials

PATENT 1, PATENT 2 and CHEST trials are currently underway at the Wesley Pulmonary Hypertension Unit and new patients are required.  We are trialing Riociuguat - a direct stimulator of the soluable Guanylate Cyclase which plays a significant role in the nitric oxide pathway and is intended for the treatment of PH. The trial is in association with Bayer and Wesley Research Institute.

In PATENT 1 & 2 trials, the patient can already be on therapy with an endothelin receptor antagonists (bosentan, sitaxentan or ambrisetan) or naïve to PAH therapy.

The CHEST trial is using the same agent for non-operable chronic thromboembolic disease related PAH.  (CTEPH)

We are accepting patients now for these trials by referral.

About The Wesley Pulmonary Hypertension Unit

The Wesley Pulmonary Hypertension Unit (WPHU) has established itself as one of the largest specialised treatment centres in Queensland.  In just 18 months of operation, the clinic has reviewed patients for treatment and have been actively enrolling patients into international clinical trials.  The treatment programs include monotherapy and combination treatments in keeping with the best available therapies for PAH.

Treatments Available

All PBS funded medications for monotherapy

Combination therapy – funded or via clinical trials

Clinical Trials with WRI

PATENT 1 and 2 trials

CHEST trial

Diagnostic Procedures

Cardiac Catherterisation
Nuclear imaging
MRI and CT
Echocardiograms
Complex Lung Testing CPET
Diagnostic Sleep Studies
6 MWT


The Wesley Pulmonary Hypertension Unit multidisciplinary team includes:

Dr John Feenstra
Thoracic and Sleep Physician
P:  (07) 3876 9033
F:  (07) 3871 3222
E:  This e-mail address is being protected from spambots. You need JavaScript enabled to view it
W: www.thoracicandsleep.com.au

Dr Andrew Scott
Thoracic and Sleep Physician
P:  (07) 3876 8405
F:  (07) 3870 3212
E:   This e-mail address is being protected from spambots. You need JavaScript enabled to view it
W:  www.thoracicandsleep.com.au

Dr David Cross
Cardiologist
P:  (07) 3858 8600
F:   (07) 3870 4917
E:   This e-mail address is being protected from spambots. You need JavaScript enabled to view it
W: www.heartcarepartners.com.au

Helen Woodhouse, CNC
WPHU Coordinator
P:  0404 650 281
F:  (07) 3871 3222
E:   This e-mail address is being protected from spambots. You need JavaScript enabled to view it

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