Information for Doctors

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Thoracic Medicine

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Sleep Medicine

Latest News

A recent study has shown that adaptive servoventilation (ASV) may be harmful in heart failure patients with central sleep apnoea. The results indicated a 10% annual risk of cardiovascular death in ASV patients compared with 7.5% in the control group. The overall survival and hospitalisation rate was not different between the groups.

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Researchers find that having sleep apnea while pregnant could make the baby prone to metabolic disease as an adult. The study suggests that reoccurring oxygen deprivation, during pregnancy causes long-term changes in the offspring's liver's ability to maintain blood glucose level.

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Symptoms of depression and insomnia are the strongest predictors of having frequent nightmares, a new study concludes. A nightmare disorder may occur when repeated nightmares cause distress or impairment in social or occupational functioning.

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Navigational brain cells that help sense direction are as electrically active during deep sleep as they are during wake time, scientists have discovered. Such information could be useful in treating navigational problems associated with Alzheimer's disease and other neurological disorders.

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A team of neuropsychologists at Saarland University have shown that even a brief sleep of 45 to 60 minutes can significantly improve retention of learned material in memory

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People exposed to prolonged periods of shortened sleep have significant increases in blood pressure during nighttime hours, researchers report.

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Current trials

Patients needed for patent 1, patent 2 and chest clinical trials

PATENT 1, PATENT 2 and CHEST trials are currently underway at the Wesley Pulmonary Hypertension Unit and new patients are required.  We are trialing Riociuguat - a direct stimulator of the soluable Guanylate Cyclase which plays a significant role in the nitric oxide pathway and is intended for the treatment of PH. The trial is in association with Bayer and Wesley Research Institute.

In PATENT 1 & 2 trials, the patient can already be on therapy with an endothelin receptor antagonists (bosentan, sitaxentan or ambrisetan) or naïve to PAH therapy.

The CHEST trial is using the same agent for non-operable chronic thromboembolic disease related PAH.  (CTEPH)

We are accepting patients now for these trials by referral.

About The Wesley Pulmonary Hypertension Unit

The Wesley Pulmonary Hypertension Unit (WPHU) has established itself as one of the largest specialised treatment centres in Queensland.  In just 18 months of operation, the clinic has reviewed patients for treatment and have been actively enrolling patients into international clinical trials.  The treatment programs include monotherapy and combination treatments in keeping with the best available therapies for PAH.

Treatments Available

All PBS funded medications for monotherapy

Combination therapy – funded or via clinical trials

Clinical Trials with WRI

PATENT 1 and 2 trials

CHEST trial

Diagnostic Procedures

Cardiac Catherterisation
Nuclear imaging
MRI and CT
Echocardiograms
Complex Lung Testing CPET
Diagnostic Sleep Studies
6 MWT


The Wesley Pulmonary Hypertension Unit multidisciplinary team includes:

Dr John Feenstra
Thoracic and Sleep Physician
P:  (07) 3876 9033
F:  (07) 3871 3222
E:  This e-mail address is being protected from spambots. You need JavaScript enabled to view it
W: www.thoracicandsleep.com.au

Dr Andrew Scott
Thoracic and Sleep Physician
P:  (07) 3876 8405
F:  (07) 3870 3212
E:   This e-mail address is being protected from spambots. You need JavaScript enabled to view it
W:  www.thoracicandsleep.com.au

Dr David Cross
Cardiologist
P:  (07) 3858 8600
F:   (07) 3870 4917
E:   This e-mail address is being protected from spambots. You need JavaScript enabled to view it
W: www.heartcarepartners.com.au

Helen Woodhouse, CNC
WPHU Coordinator
P:  0404 650 281
F:  (07) 3871 3222
E:   This e-mail address is being protected from spambots. You need JavaScript enabled to view it

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